One of the problems with genetic research is lack of DNA. Numerous family-related DNA samples are required for research into any one disease, and it has previously been impossible to check back through whole families of a breed because owners and breeders often lose touch. It may be possible to get DNA from the parents of an animal being tested, but it is less likely that the grandparents will still be available and very unlikely that the great grandparents will be around. Even some of the siblings of the present generation may be impossible to find.

Some breeders may find the idea of DNA sampling especially difficult, perhaps because they have a fear of either themselves or their stock being ostracised. This might have been a reasonable fear in the past but, as genetic testing allows even affected animals to be bred from, there is no reason now to be wary of having your breeding identified. Quite the opposite, in fact, since you will be doing so much towards helping the future of your breed.

The Animal Health Trust is encouraging all breeds to set up breed-specific DNA Archives, where swab samples can be stored for future research in the event of a previously unknown breed-related inherited problem coming to light.

The main health issues in Rough Collies are Hip Dysplasia, Eyes (PRA & CEA) and MDR1 (multi-drug resistance), and we already have genetic tests for CEA & GPRA rcd2 (Optigen) and MDR1 (Laboklin & Genomia]. However, in the future we may never know what other genetic health issues may be added so, by having DNA samples already at their disposal, geneticists at the AHT would be able to begin research immediately. Of course funding would be required but that is another story!

The EACA has recently arranged with the AHT to establish a DNA Archive for Rough Collies and the committee has agreed to maintain a stock of DNA swabs for distribution to any Rough Collie breeder who feels they would like to have their dogs’ DNA stored for the future. Each kit includes 4 swabs with instructions for use, and the swabs must be accompanied by a copy of the dog’s 5 generation pedigree and copies of all health certificates. The AHT would appreciate a £5.00 donation per dog to cover the cost of administration, though the DNA samples are stored free of charge.

Ideally, DNA should be obtained from dogs that have either been bred from, or are likely to be bred from, and dogs that are already closely related to those that are known to be affected with inherited conditions. The more information that is submitted with each DNA sample, the more useful it is likely to be. It is important to be accurate and honest about a dog's health status and keeping the Archive updated, with any significant health changes, is most important.

The AHT needs to know the dogs clinical staus with regards to a 'specific' disease ie whether it be affected, a carrier, unaffected or unknown. If a dog, whose DNA is stored, subsequently develops any serious health condition it is imperative the owner informs the AHT so the dogs record can be kept up to date. If a dog enjoys a healthy life and lives to a ripe old age then that is also important information.

Both dog and owner's information is kept in strictest confidence although quarterly reports will be forwarded to the EACA's Health Coordinator. NO INFORMATION, OTHER THAN THE DOGS NAMES WILL BE SUPPLIED.

If you would like to support the scheme and collect DNA (buccal or cheek swabs) from your Collie family, and have them stored free of charge at the Animal Health Trust, please contact me on kcollies@ntlworld.com or collect swab kits from any of the EACA’s shows and other events.

'Owner/breeders of overseas Rough Collies can also submit their dogs' DNA for archiving but please contact Pat Hutchinson on kcollies@ntlworld.com for further information and/or swab kits'

If you wish to contact the AHT with updated information, please email caniine.genetics@aht.org.uk

Pat Hutchinson, March 2011, Health Coordinator EACA’